Insulin therapy—realising the potential
نویسندگان
چکیده
منابع مشابه
Effect of Dexamethasone, Insulin and EGF on the Myogenic Potential on Human Endometrial Stem Cell
Human endometrium contains mesenchymal stem cells (eMSC) which have the ability to differentiate into three cell lineages and the potential in therapeutic applications. We hypothesize that using environmental induction in culture media such as dexamethasone, human recombinant insulin and human epidermal growth factor (hEGF) can differentiate endometrial stem cells into myoblast. These agents ha...
متن کاملEffect of Dexamethasone, Insulin and EGF on the Myogenic Potential on Human Endometrial Stem Cell
Human endometrium contains mesenchymal stem cells (eMSC) which have the ability to differentiate into three cell lineages and the potential in therapeutic applications. We hypothesize that using environmental induction in culture media such as dexamethasone, human recombinant insulin and human epidermal growth factor (hEGF) can differentiate endometrial stem cells into myoblast. These agents ha...
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Insulin degradation is a regulated process that plays a role in controlling insulin action by removing and inactivating the hormone. Abnormalities in insulin clearance and degradation are present in various pathological conditions including type 2 diabetes and obesity and may be important in producing clinical problems. The uptake, processing, and degradation of insulin by cells is a complex pr...
متن کاملTransforming potential of the insulin receptor substrate 1.
The role of the insulin receptor substrate 1 (IRS-1) in cellular transformation was studied in R- cells, which are 3T3-like fibroblasts derived from mouse embryos with a targeted disruption of the insulin-like growth factor I receptor gene. These cells cannot be transformed by oncogenes that readily transform cells originating from wild-type littermate embryos (or other 3T3-like cells). In the ...
متن کاملThe Effect of Insulin upon Resting Membrane Potential.
An electrical potential is evoked by insertion of a glass micro-electrode, containing 3 M KC1 into a living cell. As the tip of the micro-electrode commences to penetrate the cell, there is an abrupt deflection of the base-line, visualized with an oscilloscope or other recording device, which remains stable while the microelectrode tip is inside the cell. There is an equally abrupt return to th...
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ژورنال
عنوان ژورنال: International Journal of Obesity
سال: 2004
ISSN: 0307-0565,1476-5497
DOI: 10.1038/sj.ijo.0802742